Inflammatory spine diseases
Inflammatory spine diseases encompass a group of conditions characterized by inflammation of the structures of the spine, including the vertebrae, intervertebral discs, facet joints, and surrounding soft tissues. These conditions often lead to chronic pain, stiffness, and impaired mobility, significantly impacting patients' quality of life. Some of the most common inflammatory spine diseases include ankylosing spondylitis, psoriatic arthritis, and rheumatoid arthritis. Ankylosing spondylitis (AS) is a chronic inflammatory disease primarily affecting the sacroiliac joints and the spine, leading to progressive fusion of the vertebrae and reduced spinal mobility. It typically manifests with lower back pain and stiffness, which worsens with rest and improves with physical activity. AS may also involve other joints, eyes, and organs, and it is strongly associated with the HLA-B27 genetic marker. Psoriatic arthritis (PsA) is a type of inflammatory arthritis that affects individuals with psoriasis, a chronic skin condition characterized by red, scaly patches. PsA can involve the spine, leading to inflammation of the sacroiliac joints and the spine itself, causing pain, stiffness, and reduced range of motion. PsA can also affect other joints, skin, nails, and even the eyes. Rheumatoid arthritis (RA) is a systemic autoimmune disease that primarily affects the joints, causing inflammation, pain, and joint damage. While RA typically affects peripheral joints such as the hands and feet, it can also involve the cervical spine, leading to instability, subluxation, and compression of the spinal cord or nerve roots. This can result in symptoms such as neck pain, weakness, numbness, and tingling in the arms and hands.
- Ankylosing spondylitis
- Psoriatic arthritis
- Enteropathic arthritis
- Reactive arthritis
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