Scientific Program

Conference Series Ltd invites all the participants across the globe to attend 8th International Conference on Spine and Spinal Disorders Vienna, Austria.

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Scientific Program Day 1

Day 1 :

Keynote Forum

Sajad Hassanzadeh

Iran University of Medical Sciences, Iran

Keynote: More attention on glial cells to have better recovery after spinal cord injury

Time : 10:00-10:40

Biography:

Abstract:

Functional improvement after spinal cord injury remains an unsolved diffculty. Glial scars, a major component of SCI lesions, are very effective in improving the rate of this recovery. Such scars are a result of complex interaction mechanisms involving three major cells, namely, astrocytes, oligodendrocytes, and microglia. In recent years, scientists have identifed two subtypes of reactive astrocytes, namely, A1 astrocytes that induce the rapid death of neurons and oligodendrocytes, and A2 astrocytes that promote neuronal survival. Moreover, recent studies have suggested that the macrophage polarization state is more of a continuum between M1 and M2 macrophages. M1 macrophages that encourage the inflammation process kill their surrounding cells and inhibit cellular proliferation. In contrast, M2 macrophages promote cell proliferation, tissue growth, and regeneration. Furthermore, the ability of oligodendrocyte precursor cells to differentiate into adult oligodendrocytes or even neurons has been reviewed. Here, we frst scrutinize recent fndings on glial cell subtypes and their benefcial or detrimental effects after spinal cord injury. Second, we discuss how we may be able to help the functional recovery process after injury.

  • Spine and Spinal Disorders
Location: Webinar

Session Introduction

Endang Pati Broto

Dr. Soetomo General Academic Hospital, indonesia

Title: The Epidemiology of Spinal Fractures in A Level 1 Trauma Center In Indonesia
Biography:

Abstract:

Objectives: Spinal fractures are a public health issue with high morbidity and mortality, and significant social and economic impact. The burden of disease can be minimized through effective management and preventive strategies based on basic epidemiological figures. Therefore, this study aimed to establish the epidemiological figures for injuries of the spine that have been operated.
 
Methods: Data from 2014 to 2021 of spinal fractures were analyzed from the Department of Neurosurgery, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. The authors recorded and reviewed the prevalence, associated risk factors, management of spinal fractures
and output.
 
Results: The study included 111 patients with spinal fractures who were operated on the emergency operating room (23 patients) and in the central operating room (88 patients). There
were 79 male (71.2%), with the highest range at the 41-60 years old, 40.5%. The most prevalent mechanism of injury was falling down from a height of 44 patients (39.6%) followed by road traffic accidents at 29.7% (33 patients). The cervical spine was the most prevalent fracture site, followed by the thoracic spine at 37.8% and 32.4% respectively. Of all spinal fractures 91.8 %
were unstable fractures, 79.2% underwent posterior stabilization. The mortality rate associated with spinal fractures is 16.2% from trauma cases admitted to Soetomo Hospital undergoing surgery. Patients' sex, fracture anatomical site, and the mechanism of injury were identified as risk factors (p<0.05).
 
Conclusion: The established epidemiological figures for spinal fractures can be used to direct
management and preventive strategies and assist health care planning and delivery.

Rifqi Aulia Destiansyah

Soetomo Academic General Hospital, Indonesia

Title: One-stage Anterior Approach for Long-segment Subaxial Cervical Spondylitis Tuberculosis: A Case Report
Biography:

Abstract:

Background Cervical spondylitis TB is a rare disease, that may lead to severe neurological complications. The anterior approach is considered as a gold standard for cervical spine tuberculosis. Although, nowadays, available studies and literatures have not precisely mentioned on how many levels is acceptable for this disease, and is still up for discussions.

Case presentation A 45-year-old Indonesian male brought from a rural hospital to our outpatient clinic. Before admission, the patient had a progressive weakness of all extremities for 3 months. Cervical x-ray and MRI showed 3-levels of vertebral body destruction, suggesting a cervical spondylitis TB. Patient had debridement, corpectomy on C4,5,6, fusion with cage, and anterior plating from C3 to Th1 in a one-stage anterior approach.

Conclusion Anterior approach for more than two levels of affected vertebrae on cervical spondylitis TB provides respectable correction of kyphosis curvature and neurological function improvements.

 

Fachriy Balafif

Dr. Soetomo General Academic Hospital, Indonesia

Title: LUMBAR DISC HERNIATION IN A 15-YEAR-OLD GIRL: A CASE REPORT
Biography:

Abstract:

Objectives:

  • Reporting a rare case of pediatric lumbar disc herniation.
  • Describing the use of microdiscectomy for the management of pediatric lumbar disc herniation.

 

Introduction: Lumbar disc herniation (LDH) is uncommon in the pediatric population. The lumbar spine biodynamics and architecture change with age, with adults being more susceptible to LDH than children. When conservative treatment fails for pediatric LDH, surgery may be considered. We described an unusual instance of pediatric lumbar disc herniation that was successfully treated with microdiscectomy.

Case presentation: A 15-year-old patient presented with back discomfort and pain in her left leg that had been deteriorating for over 4 years. Conservative treatment with nonsteroidal anti-inflammatory medications and piriformis injection is ineffective. An MRI of her lumbosacral spine revealed that the left L4 root was compressed by a disc herniation at the L4/L5 level. A microdiscectomy was performed on the patient. Within 48 h of surgery, the patient was released home with significant alleviation in sciatic discomfort.

Discussion: In the pathogenesis of LDH, trauma and a sedentary lifestyle are important factors. Back pain and radiating pain are typical LDH symptoms. If conservative treatment does not result in a positive outcome, the microdiscectomy procedure is the surgical approach of choice. Long-term outcomes have demonstrated the efficacy and safety of this procedure.

Conclusion: Every child who presents with back pain or radiculopathy should undergo a thorough evaluation for LDH especially if they have a high body mass index or a history of trauma. Careful patient selection and preoperative evaluation result in extremely excellent surgery outcomes in pediatric LDH.